Psoriatic disease is a systemic autoimmune disease that predominately affects, the skin, the joints or both.
The two autoimmune diseases that fall under psoriatic disease are Psoriasis (PsO) and Psoriatic Arthritis (PsA).
Psoriatic disease is:
- Chronic – Psoriatic disease cannot be cured.
- Noncommunicable – Psoriatic disease is not contagious.
- Painful – Chronic inflammation leads to pain, especially in joints and lower back.
- Disfiguring – Psoriatic disease can lead to permanent disfigurement.
- Disabling – If left untreated, or treated incorrectly, chronic inflammation can lead to permanent disability
- Inflammatory – Psoriatic disease is an immune-mediated disease where chronic inflammation causes damage in multiple body sites and may lead to depression.
Skin and joint symptoms are different manifestations of the same disease. A third of people with skin manifestations (psoriasis) will develop a type of inflammatory arthritis affecting joints and tendons (psoriatic arthritis). Some people may develop joint symptoms before skin lesions appear.
In addition to skin and joint symptons, psoriatic disease is associated with a number of commorbidities.
What commorbidities are associated with psoriatic disease?
Psoriatic disease should no longer be treated as a disease that solely affects the skin and joints, but rather as a complex multisystem disorder of chronic inflammation. Whilst skin is the most visibly affected organ, there is increasing evidence of the recognition of many associated disorders.